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What is CT-FFR?

A computed tomography–fractional flow reserve (CT-FFR) test is a noninvasive method for evaluating blood flow through vessels affected by coronary artery disease. Using a cardiac computer tomography angiography (CTA) scan, advanced technology creates a 3D image that shows the extent of blood flow restriction through any potential blockages.

Coronary artery disease is caused by plaque buildup in the walls of the arteries that supply blood to the heart. The plaque, made up of cholesterol and other substances, causes the inside of the arteries to narrow and possibly block blood flow to the heart. Coronary artery disease can lead to a heart attack.

Identifying those blockages and their severity is a key part of deciding whether your coronary artery disease can be managed with medication, a minimally invasive procedure or heart surgery.

Norton Heart & Vascular Institute was the first in Louisville to offer CT-FFR as an option for advanced imaging analysis. Advanced imaging equipment at all four of Norton Healthcare’s adult-service hospitals in Louisville allows for the highest level of cardiac imaging available.

CT-FFR is new technology that analyzes a cardiac CTA scan to produce highly accurate, 3D images showing where blockages are located and how much they are restricting blood flow.

Norton Heart & Vascular Institute was the first in Louisville to offer this advanced imaging analysis to patients. Norton Heart & Vascular Institute has been using CT-FFR clinically since April 2020 and has been involved in research studies of CT-FFR. Norton Heart & Vascular Institute participated in the PRECISE trial and currently is participating in the RevealPlaque Trial. This experience has given the team expertise in this advanced technology.

The detail provided by CT-FFR previously was available only from a cardiac catheterization or a coronary angiogram. Angiograms are still the right option for many patients, but CT-FFR using HeartFlow technology allows many patients to have accurate imaging without an invasive procedure.

How It Works

Using your cardiac CTA scan, the HeartFlow technology creates a personalized digital 3D model of your coronary arteries. The HeartFlow analysis calculates how much each blockage limits your blood flow.

  • A coronary CTA scan is taken, and if more information is needed, your cardiologist may use the images to perform a HeartFlow analysis. You won’t need a new appointment or need to take any steps.
  • The HeartFlow technology will use the CT scan to create a digital 3D model of your coronary arteries and use the fundamentals of fluid dynamics to calculate how much each blockage limits your blood flow.
  • Your cardiologist will receive a color-coded 3D image of your coronary arteries to help determine the next step in your treatment plan.

How Long Does CT-FFR Take?

After a CTA scan, which typically takes about 10 minutes, providers with expertise in advanced imaging apply CT-FFR analysis to the results. Results from CT-FFR are typically available in 24 to 48 hours.

What Is Plaque Analysis?

Plaque analysis allows your care team to give you an accurate assessment of your risk of coronary artery disease, as well as a personalized treatment plan. Gathering data on the placement and type of plaque helps your physicians get a comprehensive understanding of your heart and arteries, which they use to provide precise care.

Most major insurers, including Medicare, cover the HeartFlow analysis.

Read More

It would have been a surprise heart attack, but new imaging technology revealed a hidden danger

The CT-FFR stands out in stories like Tony Seadler’s because of its ability to find something other tests can miss. In Tony’s case, it immediately showed a blockage in his circumflex coronary artery.

About Norton Heart & Vascular Institute

Norton Heart & Vascular Institute offers advanced care at all of our adult-service hospitals to save hearts and lives.

Awards and Accreditations

  • All of Norton Healthcare’s adult-service hospitals in Louisville have received Chest Pain Center accreditation from the American College of Cardiology (ACC).
  • Norton Audubon Hospital has been named a HeartCare Center National Distinction of Excellence year after year by the American College of Cardiology. This is the only hospital in Louisville to be recognized for this distinction.
  • Norton Audubon Hospital, Norton Brownsboro Hospital and Norton Hospital all are recognized as having ACC Chest Pain Center with Primary PCI accreditation.
  • Norton Audubon Hospital earned ventricular assist device (VAD) accreditation from DNV and the Centers for Medicare & Medicaid Services.

Leading the Region in Advanced Care

  • First in Louisville to implant a dual-chamber leadless pacemaker
  • First in Louisville to use PASCAL and MitraClip to replace and repair heart valves
  • First health care system in Louisville to offer CathWorks FFRangio System in a minimally invasive procedure used to treat clogged arteries and advance heart disease
  • Highest survival rate in the nation for  extracorporeal membrane oxygenation (ECMO) interventions treating heart failure
  • Among the highest survival rates in the nation for treatment of cardiogenic shock in heart failure
  • Over 100 transcarotid artery revascularization (TCAR) procedures performed for heart disease patients
  • System with the most facilities across the city of Louisville with the ability treat a life-threatening heart attack
  • More than 100 board-certified physicians and advanced practice providers with specialized heart and vascular training and experience at nearly 30 locations in Louisville and Southern Indiana

Comprehensive Heart Care for the Whole Person

Norton Heart & Vascular Institute offers patient resources to support you and your family, including free classes for people of all ages who want to improve cardiovascular health or are living with a heart condition.

  • Cardiac rehabilitation: Our cardiac rehabilitation providers are leaders in developing and applying innovative techniques that can help you recover and resume your life.
  • Connecting Hearts for Support group: The group provides education and support to individuals who have had a heart attack, are living with a heart condition or are at risk for cardiovascular disease.
  • Heart health screenings: Prevention is the best way to manage heart disease, and screenings are available to detect early signs of cardiac and vascular disease and identify risk factors.

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